Ib qho kev tivthaiv tshiab AA-MP-I tau raug cais tawm ntawm Agkistrodon acutus venom los ntawm thiophilic chromatography, Sephadex G-75, xiav gel thiab POROS HQ 20 ion pauv chromatography.Lub enzyme yog monomer protein nrog ib tug hnyav molecular ntawm 22.9 kDa, nrog ib tug isoelectric point ntawm 5.55, tsis muaj nruab nrab suab thaj pawg, thiab nws cov N-terminal sequence yog STEFQRYMEIVVDHSMVK.Cov txiaj ntsig tau pom tias nws yog ib qho tshiab PI metalloproteinase, rhiab heev rau qhov kub thiab txias, muaj kev ua haujlwm tiv thaiv coagulant, kev ua haujlwm anticoagulant muaj zog tshaj plaws ntawm 40 ℃, muaj hemorrhagic toxicity, thiab tsis muaj phospholipase A: kev ua haujlwm.
Post lub sij hawm: Dec-20-2022