Kev sib cais ntawm anticoagulant thiab fibrinolytic Cheebtsam los ntawm Agkistrodon acutus venom thiab lawv cov teebmeem ntawm coagulation system
Lub Hom Phiaj: Kawm txog cov txiaj ntsig ntawm purified thrombin zoo li enzyme thiab plasmin los ntawm Agkistrodon acutus venom ntawm cov ntshav coagulation system
Txoj kev: Thrombin zoo li enzyme thiab plasmin raug cais tawm thiab ntxuav tawm los ntawm cov venom ntawm Agkistrodon acutus los ntawm DEAE Sepharose CL-6B thiab Sephadex G-75 chromatography, thiab lawv cov teebmeem ntawm coagulation system indexes tau pom los ntawm kev sim vivo.Cov txiaj ntsig: Thrombin zoo li enzyme thiab plasmin raug cais tawm ntawm cov venom ntawm Agkistrodon acutus, thiab lawv cov txheeb ze molecular hnyav yog 39300 thiab 26600, raws li, Ob leeg thrombin zoo li enzyme thiab plasmin los ntawm Agkistrodon acutus venom tuaj yeem ua rau lub sijhawm tag nrho cov ntshav coagulation prompted, lub sij hawm, thrombin lub sij hawm thiab prothrombin lub sij hawm, thiab txo cov ntsiab lus ntawm fibrinogen, tab sis cov nyhuv ntawm thrombin zoo li enzyme muaj zog, thaum plasmin qhia anticoagulant nyhuv tsuas yog nyob rau hauv ib tug loj koob tshuaj, thiab kev sib xyaw ntawm ob yog zoo dua li lawv ib zaug siv.
Xaus:
Thrombin zoo li enzyme thiab plasmin los ntawm Agkistrodon acutus venom muaj kev cuam tshuam rau cov ntshav coagulation system hauv cov tsiaj, thiab kev sib xyaw ua ke ntawm ob qhov muaj txiaj ntsig anticoagulant.
Post lub sij hawm: May-10-2023