[Cov Lus Qhia] Lub Hom Phiaj: Kawm txog cov txiaj ntsig ntawm Agkistrodon acutus venom qog suppressor tivthaiv I (AAVC-I) ntawm kev loj hlob inhibition thiab apoptosis ntawm tib neeg lub ntsws cancer A549 hlwb.Txoj kev: Cov nqi inhibition ntawm AAVC-I ntawm qhov sib txawv ntawm A549 hlwb rau 24h thiab 48h tau ntsuas los ntawm MTT txoj kev;HE staining thiab Hoechst 33258 fluorescence staining tau siv los soj ntsuam apoptosis los ntawm morphology;Kev qhia ntawm bax protein tau kuaj pom los ntawm immunohistochemistry.Cov txiaj ntsig: MTT tau pom tias AAVC-Kuv tuaj yeem cuam tshuam qhov kev loj hlob ntawm A549 hlwb nyob rau hauv lub sij hawm-dependent thiab koob tshuaj-dependent yam;Tom qab AAVCI kev kho mob rau 24 teev, nuclear pyknosis, nuclear hyperchromatic thiab apoptotic lub cev raug soj ntsuam nyob rau hauv lub microscope;Immunohistochemistry tau pom tias qhov nruab nrab qhov muag qhov muag tau nce ntxiv nrog qhov nce ntawm cov tshuaj concentration, qhia tau hais tias qhov kev qhia ntawm bax protein tau raug tswj hwm.Xaus: Antitumor tivthaiv I ntawm Agkistrodon acutus venom tuaj yeem cuam tshuam tib neeg lub ntsws cancer A549 hlwb thiab ua rau apoptosis, uas tej zaum yuav cuam tshuam nrog kev tswj hwm ntawm bax qhia.
Post lub sij hawm: Jan-16-2023