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Kev rho tawm cov tshuaj tiv thaiv coagulant thiab fibrinolytic los ntawm Agkistrodon halys venom thiab lawv cov teebmeem ntawm cov ntshav coagulation system

Txhawm rau kawm txog cov txiaj ntsig ntawm thrombin zoo li enzyme thiab plasmin cais tawm los ntawm cov venom ntawm Agkistrodon acutus ntawm cov ntshav coagulation system Cov txheej txheem: Thrombin zoo li enzyme thiab plasmin raug cais tawm thiab ntxuav tawm ntawm Agkistrodon acutus venom los ntawm DEAE Sepharose CL-6B thiab Sephadex G-75 chromat. Lawv cov teebmeem ntawm coagulation system tau pom los ntawm hauv vivo thwmsim Cov txiaj ntsig: Thrombin zoo li enzyme thiab plasmin raug cais tawm ntawm cov venom ntawm Agkistrodon acutus, thiab lawv cov txheeb ze molecular hnyav yog 39300 thiab 26600 raws li.Hauv vivo thrombin tau pom tias thrombin zoo li enzyme thiab plasmin los ntawm Agkistrodon acutus venom tuaj yeem ua kom lub sijhawm tag nrho cov ntshav txhaws, qhib lub sijhawm prothrombin ib nrab, lub sijhawm thrombin thiab lub sijhawm prothrombin, thiab txo cov ntsiab lus ntawm fibrinogen, tab sis cov nyhuv ntawm thrombin zoo li enzyme muaj zog dua. , Txawm li cas los xij, fibrinolytic enzyme tau pom cov nyhuv anticoagulant nkaus xwb ntawm qhov ntau npaum li cas, thiab kev sib xyaw ntawm ob qho tib si zoo dua li lawv siv ib zaug.Cov ntsiab lus: Thrombin zoo li enzyme thiab fibrinolytic enzyme los ntawm Agkistrodon acutus venom muaj


Post lub sij hawm: Dec-14-2022