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Kev sib cais ntawm anticoagulant thiab fibrinolytic Cheebtsam los ntawm Agkistrodon acutus venom thiab nws cov nyhuv ntawm cov ntshav coagulation system

[Cov Lus Qhia] Lub Hom Phiaj: Kawm txog cov txiaj ntsig ntawm thrombin-zoo li thiab fibrinolytic enzymes cais thiab ntxuav los ntawm tib lub Agkistrodon acutus venom ntawm cov ntshav coagulation system.Cov txheej txheem: Cov thrombin zoo li thiab fibrinolytic enzymes raug cais thiab ntxuav los ntawm Agkistrodon acutus venom los ntawm DEAE-Sepharose CL-6B thiab Sephadex G-75 chromatography, thiab cov nyhuv ntawm ob qho tib si ntawm cov ntshav coagulation system indexes tau pom los ntawm kev sim vivo.Cov txiaj ntsig: Ib qho kev tivthaiv ntawm thrombin-zoo li thiab fibrinolytic enzymes raug cais thiab ntxuav los ntawm Agkistrodon acutus venom, Lawv qhov hnyav molecular yog 39300 thiab 26600, raws li.Hauv vivo thwmsim tau ua pov thawj tias ob qho tib si thrombin zoo li thiab fibrinolytic enzymes los ntawm Agkistrodon acutus venom tuaj yeem ua kom lub sijhawm tag nrho cov ntshav coagulation, qhib lub sijhawm prothrombin ib nrab, lub sijhawm thrombin thiab lub sijhawm prothrombin, thiab txo cov ntsiab lus ntawm fibrinogen, tab sis lub luag haujlwm ntawm thrombin- zoo li cov enzymes muaj zog, thaum cov enzymes fibrinolytic tsuas pom cov nyhuv anticoagulant ntawm koob tshuaj loj, Cov ntsiab lus: Thrombin-zoo li enzyme thiab fibrinolytic enzyme los ntawm Agkistrodon acutus venom muaj kev cuam tshuam rau cov ntshav coagulation system nyob rau hauv cov tsiaj, thiab kev sib xyaw ntawm ob muaj cov nyhuv anticoagulant pom tseeb.


Post lub sij hawm: Jan-19-2023