[Cov Lus Qhia] Lub Hom Phiaj Los soj ntsuam cov nyhuv inhibitory ntawm me me molecular polypeptide feem (K feem) los ntawm Agkistrodon acutus venom ntawm kev loj hlob ntawm tib neeg lub zes qe menyuam kab mob qog noj ntshav A2780 thiab nws cov txheej txheem.Txoj kev MTT kev soj ntsuam tau siv los txheeb xyuas qhov kev loj hlob inhibition ntawm K tivthaiv ntawm cov kab mob qog noj ntshav;Cov nyhuv anti-cell adhesion ntawm K tivthaiv tau pom los ntawm kev kuaj adhesion;AO-EB ob chav fluorescence staining thiab ntws cytometry tau siv los xyuas qhov tshwm sim ntawm apoptosis.Cov txiaj ntsig K tivthaiv inhibited kev loj hlob ntawm tib neeg lub zes qe menyuam kab mob qog noj ntshav A2780 hauv kev sib raug zoo ntawm lub sijhawm thiab koob tshuaj, thiab tuaj yeem tiv thaiv cov adhesion ntawm cov hlwb rau FN.Apoptosis tau kuaj pom los ntawm AO-EB ob chav fluorescence staining thiab ntws cytometry.Xaus Cov Khoom K muaj qhov cuam tshuam loj rau kev loj hlob ntawm tib neeg lub zes qe menyuam kab mob qog noj ntshav A2780 hauv vitro, thiab nws cov txheej txheem yuav cuam tshuam rau kev tiv thaiv cell adhesion thiab induction ntawm apoptosis.
Post lub sij hawm: Jan-11-2023