Snake Venom Application Anti-cancer effect
Nrog rau kev txhim kho kev tshawb fawb thiab thev naus laus zis, ntau thiab ntau tus neeg tau kawm txog nab venom
Ntau cov khoom siv ib leeg muaj cov haujlwm tiv thaiv kabmob, thiab lawv cov txheej txheem ntawm kev ua haujlwm tuaj yeem faib dav dav
Muaj peb yam:
(1) ionin, nws lub luag haujlwm tseem ceeb yog inhibit qog
Vascular hyperplasia thiab adhesion ntawm cov qog;
(2) Cytotoxin, ncaj qha
Nws yog siv los tua cov hlwb los ntawm cov qog nqaij hlav qog nqaij hlav;
(3) Ua rau apoptosis.thaum
Anti-cancer zog kuj tau yav tas los pom nyob rau hauv pit viper venom.Duan Tao et al los ntawm Guangxi Jian
Ib qho cytotoxin I 3-H3 raug cais tawm ntawm cov venom ntawm agkistrodon halys thiab kab lis kev cai hauv vitro
Tib neeg mob ntsws cancer cell kab (A549), human gastric cell kab (BG C) thiab human nasopharyngeal carcinoma cell line (KB)
Siv.Zhang Liang et al.cais ob yam tshuaj tiv thaiv kab mob A los ntawm venom ntawm Agkistrodon agkistrodon nyob rau yav qab teb Anhui
CTX-6 thiab ACTX-8 tau sim tawm tsam tib neeg lub ntsws qog nqaij hlav hlwb (A 5 4)
9) Qhov tseem ceeb tshaj plaws, thiab zoo thermal stability.Lei Danqing thiab lwm tus los ntawm agkistrodon venom
Ib qho me me molecule polypeptide K tivthaiv tau cais tawm ntawm qaib embryo allantoic membrane
Lub luag haujlwm ntawm angiogenesis muaj peev xwm ua kom muaj zog tiv thaiv qog angiogenesis
Peptide.Li Yingxin et al tau kawm txog cov txiaj ntsig ntawm K tivthaiv ntawm tib neeg lub zes qe menyuam qog noj ntshav hauv vitro
Kev loj hlob ntawm hom A 277 80 tau cuam tshuam loj heev, thiab cov txheej txheem ua tau
Nws yog txuam nrog anti-cell adhesion thiab inducing apoptosis.
4) Lwm yam physiological teebmeem
Agkistrodon venom kuj tau pom los txhim kho microcirculation, txo cov ntshav siab, thiab txo qis kev ceeb toom
Toxic teebmeem.Linzhentao thiab lwm tus raug cais tawm ntawm agkistrodon venom nrog dilation
Microvascular, cov khoom ntawm kev txo cov ntshav siab, nws cov txheej txheem ntawm kev ua haujlwm yuav cuam tshuam nrog
Inhibits platelet aggregation thiab inhibits platelet calcium influx thiab calcium mobilization, yog li
Txo cov concentration ntawm dawb calcium ion hauv platelet cytoplasm.Li Wande et al
Nws tau pom tias agkistrodon viper venom muaj qhov cuam tshuam sai sai ntawm postsynaptic ntawm cov paj hlwb ntawm cov toad.
Muaj peev xwm (F -EPS P) muaj cov nyhuv inhibitory.Chen Xingzhi et al.pom tias hauv
He-la hlwb thiab TH P-1 hlwb ntawm Agkistrodon halys venom
Qhov feem pua ntawm tachyzoites kis T. gondii tau nce ntau.
