Daim Ntawv Thov Ntawm Nab Venom Kom Tsis Txhob Ntshav Thiab Anticoagulation Featured Duab

Daim ntawv thov ntawm nab venom kom tsis txhob los ntshav thiab Anticoagulation

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Nyob rau hauv 1981, lub defibrase muab rho tawm thiab tsim los ntawm Kunming lub koom haum ntawm Zoology, Yunnan, Tuam Tshoj, los ntawm cov venom ntawm Suav pentameter nab dhau qhov kev ntsuam xyuas thiab tau siv nyob rau hauv kev kho mob ntawm 333 tus neeg mob vascular thrombosis, nrog rau 242 tus neeg mob cerebral thrombosis, nrog rau. kev ua tau zoo ntawm 86.4%.Lub agkistrodon agkistrodon acidase, tsim los ntawm Tuam Tshoj Medical University thiab Shenyang Pharmaceutical College, tau siv nyob rau hauv kev kho mob ntawm vascular occlusives nrog txaus siab soj ntsuam cov txiaj ntsig.Snake venom Laboratory ntawm Tuam Tshoj Medical University tsim nab venom antacid enzyme, uas yuav txo tau cov ntshav lipids, dilate cov hlab ntsha, txo cov ntsiab lus ntawm thrombin nyob rau hauv cov ntshav, nce prostacyclin, thiab so kom txaus cov nqaij mos ntawm cov hlab ntsha.Nws yog ib qho zoo tagnrho anticoagulant thrombolytic npaj.

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1. "defibrase" muab rho tawm thiab tsim los ntawm cov venom ntawm Suav pentapodes tau pom zoo los ntawm Kunming Institute of Zoology, Yunnan, Tuam Tshoj xyoo 1981. Nws tau siv rau hauv kev kho mob ntawm 333 tus neeg mob vascular thrombosis, suav nrog 242 tus neeg mob cerebral thrombosis, nrog rau kev kho mob. kev ua tau zoo ntawm 86.4%.
2. Agkistrodon agkistrodon acidase, tsim ua ke los ntawm Tuam Tshoj Medical University thiab Shenyang Pharmaceutical College, tau ua tiav cov txiaj ntsig zoo hauv kev kho mob vascular occlusives.
3. Snake venom Laboratory ntawm Tuam Tshoj Medical University tsim nab venom antacid enzyme, uas yuav txo tau cov ntshav lipids, dilate cov hlab ntsha, txo cov ntsiab lus ntawm thrombin nyob rau hauv cov ntshav, nce prostacyclin, thiab so kom txaus cov nqaij mos ntawm cov hlab ntsha.Nws yog ib qho zoo tagnrho anticoagulant thrombolytic npaj.
4. Anti-tsib-kauj ruam nab venom
Antivenomous nab serum yog ib hom tshuaj, uas yog ib qho kev txhaj tshuaj lom neeg ua los ntawm nees plasma txhaj tshuaj nrog agkistrodon (agkistrodon) toxin, zom los ntawm enzyme thiab salted tawm.Nws muaj 2000U antivenomous nab serum.Cov kab mob no tau npaj los ntawm kev zom cov enzyme thiab salting tawm ntawm nees plasma txhaj tshuaj lom los ntawm A. agkistrodon.

5. Kev lag luam-university-kev tshawb fawb kev koom tes
Mashan Longshe Snake Industry Co., Ltd. tau koom tes nrog nab Venom lub koom haum ntawm Guangxi Medical University muab cov khoom zoo nab venom rau lub sij hawm ntev, uas yog siv rau kev kawm txog biochemistry, molecular biology thiab pharmacology ntawm nab venom protein, thiab tau tswj hwm ntau dua 10 txoj haujlwm xws li National Natural Science Foundation thiab Guangxi Science thiab Technology Department cov haujlwm.Nws tau yeej qhov khoom plig thib ob ntawm Guangxi Science thiab Technology Progress Award thiab ib qho khoom plig thib peb ntawm Guangxi Science thiab technology Progress Award.

6. Snake hemagglutinin yog ib tug hemostatic tus neeg sawv cev nrog ib tug thrombin kinase zoo li cov nyhuv, uas yuav hloov mus rau hauv fibrin los ntawm hydrolyzing fibrinogen, yog li pab txhawb lub cev coagulation muaj nuj nqi;Cov khoom no kuj muaj kev ua haujlwm ntawm kev txhim kho platelet aggregation, uas tuaj yeem ua rau tsis muaj kev sib sau ua ke ntawm platelets, yog li txhim kho cov coagulation muaj nuj nqi, tab sis tsis txhawb platelet aggregation hauv cov hlab ntsha tsis zoo.
Hemocoagulation ntawm agkistrodon agkistrodon ua ib qho kev pab rau hemostasis ntawm qhov txhab sab nrauv hauv kev phais.